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Highly efficient gene knockout by injection of TALEN mRNAs into oocytes and host transfer in Xenopus laevis
Zinc-finger nucleases, transcription activator-like effector nucleases (TALENs) and the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins) system are potentially powerful tools for producing tailor-made knockout animals. However, their mutagenic activit...
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| Publicado en: | Biol Open |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365486/ https://ncbi.nlm.nih.gov/pubmed/25596277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410009 |
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