Mutations in the DI-DII Linker of Human Parainfluenza Virus Type 3 Fusion Protein Result in Diminished Fusion Activity

Human parainfluenza virus type 3 (HPIV3) can cause severe respiratory tract diseases in infants and young children, but no licensed vaccines or antiviral agents are currently available for treatment. Fusing the viral and target cell membranes is a prerequisite for its entry into host cells and is di...

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Pubblicato in:PLoS One
Autori principali: Xie, Wenyan, Wen, Hongling, Chu, Fulu, Yan, Shaofeng, Lin, Bin, Xie, Wenli, Liu, Ying, Ren, Guijie, Zhao, Li, Song, Yanyan, Sun, Chengxi, Wang, Zhiyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549179/
https://ncbi.nlm.nih.gov/pubmed/26305905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136474
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