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Estrogen modulation of the ethanol-evoked myocardial oxidative stress and dysfunction via DAPK3/Akt/ERK activation in male rats

Evidence suggests that male rats are protected against the hypotensive and myocardial depressant effects of ethanol compared with females. We investigated whether E(2) modifies the myocardial and oxidative effects of ethanol in male rats. Conscious male rats received ethanol (0.5, 1 or 1.5 g/kg i.v....

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: El-Mas, Mahmoud M., Abdel-Rahman, Abdel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549171/
https://ncbi.nlm.nih.gov/pubmed/26111663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.06.015
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