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Estrogen modulation of the ethanol-evoked myocardial oxidative stress and dysfunction via DAPK3/Akt/ERK activation in male rats

Evidence suggests that male rats are protected against the hypotensive and myocardial depressant effects of ethanol compared with females. We investigated whether E(2) modifies the myocardial and oxidative effects of ethanol in male rats. Conscious male rats received ethanol (0.5, 1 or 1.5 g/kg i.v....

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Pubblicato in:Toxicol Appl Pharmacol
Autori principali: El-Mas, Mahmoud M., Abdel-Rahman, Abdel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549171/
https://ncbi.nlm.nih.gov/pubmed/26111663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.06.015
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