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Estrogen modulation of the ethanol-evoked myocardial oxidative stress and dysfunction via DAPK3/Akt/ERK activation in male rats

Evidence suggests that male rats are protected against the hypotensive and myocardial depressant effects of ethanol compared with females. We investigated whether E(2) modifies the myocardial and oxidative effects of ethanol in male rats. Conscious male rats received ethanol (0.5, 1 or 1.5 g/kg i.v....

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Appl Pharmacol
Hauptverfasser: El-Mas, Mahmoud M., Abdel-Rahman, Abdel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549171/
https://ncbi.nlm.nih.gov/pubmed/26111663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.06.015
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