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Lentinan exerts synergistic apoptotic effects with paclitaxel in A549 cells via activating ROS-TXNIP-NLRP3 inflammasome

Paclitaxel is generally used to treat cancers in clinic as an inhibitor of cell division. However, the acquired resistance in tumours limits its clinical efficacy. Therefore, the aim of this study was to detect whether co-treatment with lentinan enhanced the anti-cancer effects of paclitaxel in A549...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Liu, Wei, Gu, Jun, Qi, Jun, Zeng, Xiao-Ning, Ji, Juan, Chen, Zheng-Zhen, Sun, Xiu-Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549045/
https://ncbi.nlm.nih.gov/pubmed/25858687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12570
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