Human Blood and Mucosal Regulatory T Cells Express Activation Markers and Inhibitory Receptors in Inflammatory Bowel Disease

BACKGROUND: FOXP3(+) regulatory T cells (Tregs) are critical for preventing intestinal inflammation. However, FOXP3(+) T cells are paradoxically increased in the intestines of patients with the inflammatory bowel disease (IBD) ulcerative colitis (UC) or Crohn’s disease (CD). We determined whether th...

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Udgivet i:PLoS One
Main Authors: Lord, James D., Shows, Donna M., Chen, Janice, Thirlby, Richard C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548948/
https://ncbi.nlm.nih.gov/pubmed/26305224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136485
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