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Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo

Microvesicles shed from cells carry constituents of the cell cytoplasm, including, of importance in multidrug resistance to cancer chemotherapy, drugs that the tumor cell attempts to efflux. To see whether such drugs could be used at lower concentrations with the same efficacy, it was first shown th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jorfi, Samireh, Ansa-Addo, Ephraim A., Kholia, Sharad, Stratton, Dan, Valley, Shaunelle, Lange, Sigrun, Inal, Jameel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548233/
https://ncbi.nlm.nih.gov/pubmed/26302712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13006
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