SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease presenting as sporadic (sALS) or familial (fALS) forms. Even if the list of the genes underlining ALS greatly expanded, defects in superoxide dismutase 1 (SOD1), encoding the copper/zinc SOD1, still remain a major cause of fALS and...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Tafuri, Francesco, Ronchi, Dario, Magri, Francesca, Comi, Giacomo P., Corti, Stefania
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548205/
https://ncbi.nlm.nih.gov/pubmed/26379505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00336
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