The Non-Canonical Role of Aurora-A in DNA Replication

Aurora-A is a well-known mitotic kinase that regulates mitotic entry, spindle formation, and chromosome maturation as a canonical role. During mitosis, Aurora-A protein is stabilized by its phosphorylation at Ser51 via blocking anaphase-promoting complex/cyclosome-mediated proteolysis. Importantly,...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Tsunematsu, Takaaki, Arakaki, Rieko, Yamada, Akiko, Ishimaru, Naozumi, Kudo, Yasusei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548192/
https://ncbi.nlm.nih.gov/pubmed/26380219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00187
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