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GLT-1 Transport Stoichiometry Is Constant at Low and High Glutamate Concentrations when Chloride Is Substituted by Gluconate

Glutamate is the major excitatory neurotransmitter, but prolonged exposure even at micromolar concentrations causes neuronal death. Extracellular glutamate is maintained at nanomolar level by glutamate transporters, which, however, may reverse transport and release glutamate. If and when the reverse...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kabakov, Anatoli Y., Rosenberg, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547712/
https://ncbi.nlm.nih.gov/pubmed/26301411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136111
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