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Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators
A series of substituted 1H-indole-2-carboxamides structurally related to compounds Org27569 (1), Org29647 (2) and Org27759 (3) were synthesized and evaluated for CB1 allosteric modulating activity in calcium mobilization assays. Structure-activity relationship studies showed that the modulation pote...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547606/ https://ncbi.nlm.nih.gov/pubmed/25797163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.058 |
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