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Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy.

Antisense (AS) oligonucleotides (ONs) to galanin (GAL) were applied to the proximal end of a transected sciatic nerve, allowing their cellular uptake and transport into injured axons. GAL expression in dorsal root ganglia and self-mutilation behavior (autotomy) were then studied. AS-ONs with phospho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ji, R R, Zhang, Q, Bedecs, K, Arvidsson, J, Zhang, X, Xu, X J, Wiesenfeld-Hallin, Z, Bartfai, T, Hökfelt, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45474/
https://ncbi.nlm.nih.gov/pubmed/7528924
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