Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy.

Antisense (AS) oligonucleotides (ONs) to galanin (GAL) were applied to the proximal end of a transected sciatic nerve, allowing their cellular uptake and transport into injured axons. GAL expression in dorsal root ganglia and self-mutilation behavior (autotomy) were then studied. AS-ONs with phospho...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ji, R R, Zhang, Q, Bedecs, K, Arvidsson, J, Zhang, X, Xu, X J, Wiesenfeld-Hallin, Z, Bartfai, T, Hökfelt, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7528924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12540
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