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Galanin antisense oligonucleotides reduce galanin levels in dorsal root ganglia and induce autotomy in rats after axotomy.

Antisense (AS) oligonucleotides (ONs) to galanin (GAL) were applied to the proximal end of a transected sciatic nerve, allowing their cellular uptake and transport into injured axons. GAL expression in dorsal root ganglia and self-mutilation behavior (autotomy) were then studied. AS-ONs with phospho...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Ji, R R, Zhang, Q, Bedecs, K, Arvidsson, J, Zhang, X, Xu, X J, Wiesenfeld-Hallin, Z, Bartfai, T, Hökfelt, T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7528924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12540
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