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Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness

Up-regulation of IFN-stimulated genes (ISGs) is sustained in hepatitis C virus (HCV)-infected livers. Here, we investigated the mechanism of prolonged ISG expression and its role in IFN responsiveness during HCV infection in relation to unphosphorylated IFN-stimulated gene factor 3 (U-ISGF3), recent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sung, Pil Soo, Cheon, HyeonJoo, Cho, Chung Hwan, Hong, Seon-Hui, Park, Do Youn, Seo, Hyung-Il, Park, Su-Hyung, Yoon, Seung Kew, Stark, George R., Shin, Eui-Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547285/
https://ncbi.nlm.nih.gov/pubmed/26216956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513341112
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