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Creative template-dependent synthesis by human polymerase mu

Among the many proteins used to repair DNA double-strand breaks by nonhomologous end joining (NHEJ) are two related family X DNA polymerases, Pol λ and Pol µ. Which of these two polymerases is preferentially used for filling DNA gaps during NHEJ partly depends on sequence complementarity at the brea...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Moon, Andrea F., Gosavi, Rajendrakumar A., Kunkel, Thomas A., Pedersen, Lars C., Bebenek, Katarzyna
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547271/
https://ncbi.nlm.nih.gov/pubmed/26240373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505798112
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