Nucleotides regulate the mechanical hierarchy between subdomains of the nucleotide binding domain of the Hsp70 chaperone DnaK

The regulation of protein function through ligand-induced conformational changes is crucial for many signal transduction processes. The binding of a ligand alters the delicate energy balance within the protein structure, eventually leading to such conformational changes. In this study, we elucidate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Bauer, Daniela, Merz, Dale R., Pelz, Benjamin, Theisen, Kelly E., Yacyshyn, Gail, Mokranjac, Dejana, Dima, Ruxandra I., Rief, Matthias, Žoldák, Gabriel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547238/
https://ncbi.nlm.nih.gov/pubmed/26240360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504625112
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg