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Local axonal protection by WldS as revealed by conditional regulation of protein stability

The expression of the mutant Wallerian degeneration slow (WldS) protein significantly delays axonal degeneration from various nerve injuries and in multiple species; however, the mechanism for its axonal protective property remains unclear. Although WldS is localized predominantly in the nucleus, it...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Wang, Jack T., Medress, Zachary A., Vargas, Mauricio E., Barres, Ben A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547231/
https://ncbi.nlm.nih.gov/pubmed/26209654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508337112
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