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Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1

SIRT1 is one of seven mammalian homologs of Sir2 that catalyzes NAD(+)-dependent protein deacetylation. The aim of the present study is to explore the effect of SIRT1 small molecule activator on the anticancer activity and the underlying mechanism. We examined the anticancer activity of a novel oral...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hu, An, Huang, Jing-Juan, Li, Rui-Lin, Lu, Zhao-Yang, Duan, Jun-Li, Xu, Wei-Hua, Chen, Xiao-Ping, Fan, Jing-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547100/
https://ncbi.nlm.nih.gov/pubmed/26299580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13429
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