Kinetic parameters of the protein tyrosine kinase activity of EGF-receptor mutants with individually altered autophosphorylation sites.

Epidermal growth factor (EGF)-receptor mutants in which individual autophosphorylation sites (Tyr1068, Tyr1148 or Tyr1173) have been replaced by phenylalanine residues were expressed in NIH-3T3 cells lacking endogenous EGF-receptors. Kinetic parameters of the kinase of wild-type and mutant receptors...

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Pubblicato in:	EMBO J
Autori principali:	Honegger, A, Dull, T J, Szapary, D, Komoriya, A, Kris, R, Ullrich, A, Schlessinger, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3181128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03170.x
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