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Role of SHIP1 in iNKT cell development and functions

SH2-containing inositol phosphatase-1 (SHIP1) is a 5' inositol phosphatase known to negatively regulate the signaling product of the phosphoinositide-3 kinase (PI3K) pathway, phosphatidylinositol (3,4,5)-trisphosphate (PIP(3)). SHIP1 is recruited to a large number of inhibitory receptors expres...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Anderson, Courtney K., Salter, Alexander I., Toussaint, Leon E., Reilly, Emma C., Fugère, Céline, Srivastava, Neetu, Kerr, William G., Brossay, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546909/
https://ncbi.nlm.nih.gov/pubmed/26232432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500567
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