Over-Expression of Cysteine Leucine Rich Protein Is Related to SAG Resistance in Clinical Isolates of Leishmania donovani

BACKGROUND: Resistance emergence against antileishmanial drugs, particularly Sodium Antimony Gluconate (SAG) has severely hampered the therapeutic strategy against visceral leishmaniasis, the mechanism of resistance being indistinguishable. Cysteine leucine rich protein (CLrP), was recognized as one...

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Foilsithe in:PLoS Negl Trop Dis
Main Authors: Das, Sanchita, Shah, Priyanka, Tandon, Rati, Yadav, Narendra Kumar, Sahasrabuddhe, Amogh A., Sundar, Shyam, Siddiqi, Mohammad Imran, Dube, Anuradha
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546639/
https://ncbi.nlm.nih.gov/pubmed/26295340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003992
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