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Repurposing Hsp104 to antagonize seminal amyloid and counter HIV infection
Naturally occurring proteolytic fragments of prostatic acid phosphatase (PAP248-286 and PAP85-120) and semenogelins (SEM1 and 2) form amyloid fibrils in seminal fluid, which capture HIV virions and promote infection. For example, PAP248-286 fibrils, termed SEVI (Semen derived Enhancer of Viral Infec...
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| Gepubliceerd in: | Chem Biol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546571/ https://ncbi.nlm.nih.gov/pubmed/26256479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.07.007 |
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