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Cycloadditions of 1,2,3-Triazines Bearing C5-Electron Donating Substituents: Robust Pyrimidine Synthesis

[Image: see text] The examination of the cycloaddition reactions of 1,2,3-triazines 17–19, bearing electron-donating substituents at C5, are described. Despite the noncomplementary 1,2,3-triazine C5 substituents, amidines were found to undergo a powerful cycloaddition to provide 2,5-disubstituted py...

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Bibliographic Details
Published in:Org Lett
Main Authors: Glinkerman, Christopher M., Boger, Dale L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546508/
https://ncbi.nlm.nih.gov/pubmed/26172042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b01870
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