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NaHS Protects Cochlear Hair Cells from Gentamicin-Induced Ototoxicity by Inhibiting the Mitochondrial Apoptosis Pathway

Aminoglycoside antibiotics such as gentamicin could cause ototoxicity in mammalians, by inducing oxidative stress and apoptosis in sensory hair cells of the cochlea. Sodium hydrosulfide (NaHS) is reported to alleviate oxidative stress and apoptosis, but its role in protecting aminoglycoside-induced...

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Foilsithe in:PLoS One
Main Authors: Dong, Yaodong, Liu, Dongliang, Hu, Yue, Ma, Xiulan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546415/
https://ncbi.nlm.nih.gov/pubmed/26295804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136051
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