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Detection and Tracking of NY-ESO-1-Specific CD8(+) T Cells by High-Throughput T Cell Receptor β (TCRB) Gene Rearrangements Sequencing in a Peptide-Vaccinated Patient

Comprehensive immunological evaluation is crucial for monitoring patients undergoing antigen-specific cancer immunotherapy. The identification and quantification of T cell responses is most important for the further development of such therapies. Using well-characterized clinical samples from a high...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Miyai, Manami, Eikawa, Shingo, Hosoi, Akihiro, Iino, Tamaki, Matsushita, Hirokazu, Isobe, Midori, Uenaka, Akiko, Udono, Heiichiro, Nakajima, Jun, Nakayama, Eiichi, Kakimi, Kazuhiro
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546392/
https://ncbi.nlm.nih.gov/pubmed/26291626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136086
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