Chloroquine sensitivity: diminished prevalence of chloroquine-resistant gene marker pfcrt-76 13 years after cessation of chloroquine use in Msambweni, Kenya

BACKGROUND: Plasmodium falciparum resistance to chloroquine (CQ) denied healthcare providers access to a cheap and effective anti-malarial drug. Resistance has been proven to be due to point mutations on the parasite’s pfcrt gene, particularly on codon 76, resulting in an amino acid change from lysi...

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Detalles Bibliográficos
Publicado en:Malar J
Autores principales: Kiarie, William Chege, Wangai, Laura, Agola, Eric, Kimani, Francis T., Hungu, Charity
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546357/
https://ncbi.nlm.nih.gov/pubmed/26296743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0850-9
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