Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells

BACKGROUND: Glioblastoma (GBM) is the most common primary brain malignancy and confers a dismal prognosis. GBMs harbor glioblastoma-initiating cells (GICs) that drive tumorigenesis and contribute to therapeutic resistance and tumor recurrence. Consequently, there is a strong rationale to target this...

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Detalles Bibliográficos
Publicado en:Mol Cancer
Autores principales: Mughal, Awais A., Grieg, Zanina, Skjellegrind, Håvard, Fayzullin, Artem, Lamkhannat, Mustapha, Joel, Mrinal, Ahmed, M. Shakil, Murrell, Wayne, Vik-Mo, Einar O., Langmoen, Iver A., Stangeland, Biljana
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546247/
https://ncbi.nlm.nih.gov/pubmed/26292663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0432-z
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