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Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach

BACKGROUND: Epigenetic alterations, such as aberrant DNA methylation of promoter and enhancer regions, which lead to atypical gene expression, have been associated with carcinogenesis. In hepatocellular carcinoma (HCC), genome-wide analysis of methylation has only recently been used. For a better un...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Gao, Fei, Liang, Huifang, Lu, Hanlin, Wang, Junwen, Xia, Meng, Yuan, Zhimei, Yao, Yu, Wang, Tong, Tan, Xiaolong, Laurence, Arian, Xu, Hua, Yu, Jingjing, Xiao, Wei, Chen, Wei, Zhou, Ming, Zhang, Xiuqing, Chen, Qian, Chen, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546208/
https://ncbi.nlm.nih.gov/pubmed/26300991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0121-1
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