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High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing
DNA methylation stabilizes developmentally programmed gene expression states. Aberrant methylation is associated with disease progression and is a common feature of cancer genomes. Presently, few methods enable quantitative, large-scale, single-base resolution mapping of DNA methylation states in de...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752124/ https://ncbi.nlm.nih.gov/pubmed/19581485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.095190.109 |
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