High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

DNA methylation stabilizes developmentally programmed gene expression states. Aberrant methylation is associated with disease progression and is a common feature of cancer genomes. Presently, few methods enable quantitative, large-scale, single-base resolution mapping of DNA methylation states in de...

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Détails bibliographiques
Auteurs principaux: Hodges, Emily, Smith, Andrew D., Kendall, Jude, Xuan, Zhenyu, Ravi, Kandasamy, Rooks, Michelle, Zhang, Michael Q., Ye, Kenny, Bhattacharjee, Arindam, Brizuela, Leonardo, McCombie, W. Richard, Wigler, Michael, Hannon, Gregory J., Hicks, James B.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2009
Sujets:
Methods
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752124/
https://ncbi.nlm.nih.gov/pubmed/19581485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.095190.109
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