Crystal structure of fructose-1,6-bisphosphatase complexed with fructose 2,6-bisphosphate, AMP, and Zn2+ at 2.0-A resolution: aspects of synergism between inhibitors.

The crystal structure of fructose-1,6-bisphosphatase (Fru-1,6-Pase; EC 3.1.3.11) complexed with Zn2+ and two allosteric regulators, AMP and fructose 2,6-bisphosphate (Fru-2,6-P2) has been determined at 2.0-A resolution. In the refined model, the crystallographic R factor is 0.189 with rms deviations...

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Main Authors: Xue, Y, Huang, S, Liang, J Y, Zhang, Y, Lipscomb, W N
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45462/
https://ncbi.nlm.nih.gov/pubmed/7809062
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