Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer

BACKGROUND: PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in GBC and to establish its relation to clinical and morphological parameters and...

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Detalhes bibliográficos
Publicado no:Diagn Pathol
Main Authors: Roa, Iván, de Toro, Gonzalo, Fernández, Fernanda, Game, Anakaren, Muñoz, Sergio, de Aretxabala, Xabier, Javle, Milind
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546176/
https://ncbi.nlm.nih.gov/pubmed/26294099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0381-2
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