GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice

BACKGROUND: The plasma membranes of striated muscle cells are particularly susceptible to rupture as they endure significant mechanical stress and strain during muscle contraction, and studies have shown that defects in membrane repair can contribute to the progression of muscular dystrophy. The syn...

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Vydáno v:Skelet Muscle
Hlavní autoři: Lenhart, Kaitlin C., O’Neill, Thomas J., Cheng, Zhaokang, Dee, Rachel, Demonbreun, Alexis R., Li, Jianbin, Xiao, Xiao, McNally, Elizabeth M., Mack, Christopher P., Taylor, Joan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546166/
https://ncbi.nlm.nih.gov/pubmed/26301073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-015-0054-6
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