Bidirectional role of IL-6 signal in pathogenesis of lung fibrosis

BACKGROUND: Various signals are known to participate in the pathogenesis of lung fibrosis. Our aim was to determine which signal is predominantly mobilized in the early inflammatory phase and thereafter modulates the development of lung fibrosis. METHODS: Mice received a single dose of 3 mg/kg body...

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Veröffentlicht in:Respir Res
Hauptverfasser: Kobayashi, Takeshi, Tanaka, Kensuke, Fujita, Tetsuo, Umezawa, Hiroki, Amano, Hiroyuki, Yoshioka, Kento, Naito, Yusuke, Hatano, Masahiko, Kimura, Sadao, Tatsumi, Koichiro, Kasuya, Yoshitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546032/
https://ncbi.nlm.nih.gov/pubmed/26289430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0261-z
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