Transcriptomic changes involved in the dedifferentiation of myofibroblasts derived from the lung of a patient with idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown etiology. Under pathological conditions in lungs with IPF, myofibroblasts serve a key role in fibrogenesis via the accumulation of an excessive amount of extracellular matrix. To develop effective therapeutic interventions agains...

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Udgivet i:Mol Med Rep
Main Authors: Suzuki, Kenichi, Kim, Jun-Dal, Ugai, Keita, Matsuda, Shuichi, Mikami, Hideki, Yoshioka, Kento, Ikari, Jun, Hatano, Masahiko, Fukamizu, Akiyoshi, Tatsumi, Koichiro, Kasuya, Yoshitoshi
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339813/
https://ncbi.nlm.nih.gov/pubmed/32626975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11218
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