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LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2

High cholesterol and diabetes are major risk factors for atherosclerosis. Regression of atherosclerosis is mediated in part by the Liver X Receptor (LXR) through the induction of genes involved in cholesterol transport and efflux. In the context of diabetes, regression of atherosclerosis is impaired...

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Publicado en:PLoS One
Autores principales: Hussein, Maryem A., Shrestha, Elina, Ouimet, Mireille, Barrett, Tessa J., Leone, Sarah, Moore, Kathryn J., Hérault, Yann, Fisher, Edward A., Garabedian, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545936/
https://ncbi.nlm.nih.gov/pubmed/26288135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135218
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