DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection

BACKGROUND: The prevalence of allergic diseases are increasing worldwide, emphasizing the need to elucidate their pathogeneses. The aims of this study were to use a two-stage design to identify DNA methylation levels at cytosine–phosphate–guanine (CpG) sites across the genome associated with atopy a...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Everson, Todd M., Lyons, Genevieve, Zhang, Hongmei, Soto-Ramírez, Nelís, Lockett, Gabrielle A., Patil, Veeresh K., Merid, Simon K., Sӧderhӓll, Cilla, Melén, Erik, Holloway, John W., Arshad, S. Hasan, Karmaus, Wilfried
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545869/
https://ncbi.nlm.nih.gov/pubmed/26292806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0213-8
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