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JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia

Recent studies of acute lymphoblastic leukemia have identified activating mutations in components of the interleukin-7 receptor complex (IL7R, JAK1, and JAK3). It will be of interest to investigate both JAK1 and JAK3 kinase inhibitors as targeted agents for these leukemias.

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Degryse, Sandrine, Cools, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545857/
https://ncbi.nlm.nih.gov/pubmed/26208852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0192-7
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