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M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

BACKGROUND: Tumor associated macrophages (TAMs) are present in high density in solid tumors. TAMs share many characteristics with alternatively activated macrophages, also called M2. They have been shown to favor tumor development and a role in chemoresistance has also been suggested. Here, we inves...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Genin, Marie, Clement, Francois, Fattaccioli, Antoine, Raes, Martine, Michiels, Carine
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545815/
https://ncbi.nlm.nih.gov/pubmed/26253167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1546-9
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