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M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

BACKGROUND: Tumor associated macrophages (TAMs) are present in high density in solid tumors. TAMs share many characteristics with alternatively activated macrophages, also called M2. They have been shown to favor tumor development and a role in chemoresistance has also been suggested. Here, we inves...

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Publicat a:BMC Cancer
Autors principals: Genin, Marie, Clement, Francois, Fattaccioli, Antoine, Raes, Martine, Michiels, Carine
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545815/
https://ncbi.nlm.nih.gov/pubmed/26253167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1546-9
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