Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression

BACKGROUND: Acute myeloid leukemia (AML) with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) is a distinct clinicopathologic entity with a poor prognosis. However, double inv(3)(q21q26.2) is extremely rare in AML. We report here 3 cases analyzed by oligonucleotide microarray comparative genomic hybridization (a...

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Veröffentlicht in:Mol Cytogenet
Hauptverfasser: Gu, Jun, Patel, Keyur P., Bai, Bing, Liu, Ching-Hua, Tang, Guilin, Kantarjian, Hagop M., Tang, Zhenya, Abraham, Ronald, Luthra, Rajyalakshmi, Medeiros, L. Jeffrey, Lin, Pei, Lu, Xinyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545786/
https://ncbi.nlm.nih.gov/pubmed/26300976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-015-0171-2
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