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Pediatric chronic myeloid leukemia with inv(3)(q21q26.2) and T lymphoblastic transformation: a case report

BACKGROUND: Chronic myeloid leukemia (CML) comprises ~3 % of pediatric leukemia. Although therapy with tyrosine kinase inhibitors (TKIs) is highly effective for CML, multiple factors have been identified as predictive of treatment failure. Chromosomal abnormalities involving the MECOM locus at 3q26...

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Bibliographische Detailangaben
Veröffentlicht in:Biomark Res
Hauptverfasser: Lewen, Margaret, Gresh, Renee, Queenan, Maria, Paessler, Michele, Pillai, Vinodh, Hexner, Elizabeth, Frank, Dale, Bagg, Adam, Aplenc, Richard, Caywood, Emi, Wertheim, Gerald
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957483/
https://ncbi.nlm.nih.gov/pubmed/27453784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-016-0069-0
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