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The nucleic acid-sensing inflammasomes

Inflammasomes are oligomeric signaling complexes that promote caspase activation and maturation of proinflammatory cytokines. Structural and biophysical studies have shed light on the mechanisms of nucleic acid recognition and signaling complex assembly involving the AIM2 (absent in myeloma 2) and I...

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Bibliografiske detaljer
Udgivet i:Immunol Rev
Hovedforfatter: Xiao, Tsan Sam
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545668/
https://ncbi.nlm.nih.gov/pubmed/25879287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12281
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