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Searching for Grendel: origin and global spread of the C9ORF72 repeat expansion

Recent advances are uncovering more and more of the genetic architecture underlying amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative condition that affects ~6,000 Americans annually. Chief among these was the discovery that a large repeat expansion in the C9ORF72 gene is responsible fo...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol
Main Authors: Pliner, Hannah A., Mann, David M., Traynor, Bryan J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545603/
https://ncbi.nlm.nih.gov/pubmed/24496499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1250-x
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