A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists

Inhibition of acetylcholinesterase (AChE) after nerve agent exposure induces status epilepticus (SE), which causes brain damage or death. The development of countermeasures appropriate for the pediatric population requires testing of anticonvulsant treatments in immature animals. In the present stud...

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Détails bibliographiques
Publié dans:Toxicol Appl Pharmacol
Auteurs principaux: Miller, Steven L., Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Prager, Eric M., Almeida-Suhett, Camila P., Apland, James P., Braga, Maria F.M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545593/
https://ncbi.nlm.nih.gov/pubmed/25689173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.02.008
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