A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists

Inhibition of acetylcholinesterase (AChE) after nerve agent exposure induces status epilepticus (SE), which causes brain damage or death. The development of countermeasures appropriate for the pediatric population requires testing of anticonvulsant treatments in immature animals. In the present stud...

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Udgivet i:Toxicol Appl Pharmacol
Main Authors: Miller, Steven L., Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Prager, Eric M., Almeida-Suhett, Camila P., Apland, James P., Braga, Maria F.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545593/
https://ncbi.nlm.nih.gov/pubmed/25689173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.02.008
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