Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

Compensatory proliferation triggered by hepatocyte loss is required for liver regeneration and maintenance but also promotes development of hepatocellular carcinoma (HCC). Despite extensive investigation, the cells responsible for hepatocyte restoration or HCC development remain poorly characterized...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Font-Burgada, Joan, Shalapour, Shabnam, Ramaswamy, Suvasini, Hsueh, Brian, Rossell, David, Umemura, Atsushi, Taniguchi, Koji, Nakagawa, Hayato, Valasek, Mark A., Ye, Li, Kopp, Janel L., Sander, Maike, Carter, Hannah, Deisseroth, Karl, Verma, Inder M., Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545590/
https://ncbi.nlm.nih.gov/pubmed/26276631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.026
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