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Outcome Assessments in Clinical Trials of Cryptococcal Meningitis: Considerations on Use of Early Fungicidal Activity as a Potential Surrogate Endpoint for All-Cause Mortality

Cryptococcal meningitis (CM) is a common disease in resource-challenged settings, with a high mortality within weeks of disease onset. Mortality remains high with current treatments, so more effective interventions are needed to decrease mortality. There has been interest in using the outcome assess...

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Bibliografski detalji
Izdano u:Curr Treat Options Infect Dis
Glavni autori: Montezuma-Rusca, Jairo Mauricio, Powers, John H.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545574/
https://ncbi.nlm.nih.gov/pubmed/26306077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40506-014-0026-0
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