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Outcome Assessments in Clinical Trials of Cryptococcal Meningitis: Considerations on Use of Early Fungicidal Activity as a Potential Surrogate Endpoint for All-Cause Mortality
Cryptococcal meningitis (CM) is a common disease in resource-challenged settings, with a high mortality within weeks of disease onset. Mortality remains high with current treatments, so more effective interventions are needed to decrease mortality. There has been interest in using the outcome assess...
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| Published in: | Curr Treat Options Infect Dis |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545574/ https://ncbi.nlm.nih.gov/pubmed/26306077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40506-014-0026-0 |
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