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Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle

Many proteins are known to promote ciliogenesis, but mechanisms that promote primary cilia disassembly before mitosis are largely unknown. Here we identify a mechanism that favours cilium disassembly and maintains the disassembled state. We show that co-localization of the S/G2 phase kinase, Nek2 an...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Kim, Sehyun, Lee, Kwanwoo, Choi, Jung-Hwan, Ringstad, Niels, Dynlacht, Brian David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545512/
https://ncbi.nlm.nih.gov/pubmed/26290419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9087
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