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Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle

Many proteins are known to promote ciliogenesis, but mechanisms that promote primary cilia disassembly before mitosis are largely unknown. Here we identify a mechanism that favours cilium disassembly and maintains the disassembled state. We show that co-localization of the S/G2 phase kinase, Nek2 an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Kim, Sehyun, Lee, Kwanwoo, Choi, Jung-Hwan, Ringstad, Niels, Dynlacht, Brian David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Pub. Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545512/
https://ncbi.nlm.nih.gov/pubmed/26290419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9087
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