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Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle
Many proteins are known to promote ciliogenesis, but mechanisms that promote primary cilia disassembly before mitosis are largely unknown. Here we identify a mechanism that favours cilium disassembly and maintains the disassembled state. We show that co-localization of the S/G2 phase kinase, Nek2 an...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Pub. Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545512/ https://ncbi.nlm.nih.gov/pubmed/26290419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9087 |
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