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Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle

Many proteins are known to promote ciliogenesis, but mechanisms that promote primary cilia disassembly before mitosis are largely unknown. Here we identify a mechanism that favours cilium disassembly and maintains the disassembled state. We show that co-localization of the S/G2 phase kinase, Nek2 an...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Sehyun, Lee, Kwanwoo, Choi, Jung-Hwan, Ringstad, Niels, Dynlacht, Brian David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545512/
https://ncbi.nlm.nih.gov/pubmed/26290419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9087
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